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Recombinant Rat GRO alpha/CXCL1
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性状 | Recombinant Rat GRO alpha/CXCL1 在炎症、血管生成、肿瘤发生和伤口愈合中起重要作用。
Synonyms rRtGRO-α/CXCL1; Growth-regulated alpha protein; C-X-C motif chemokine 1; CINC-1 ; 重组大鼠CXC 趋化因子1 Species Rat Source E. coli Accession P14095 Gene ID 81503 Molecular Weight Approximately 7.8 kDa AA Sequence APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK Biological Activity Full biological activity determined by a chemotaxis bioassay using rat neutrophils is in a concentration range of 10-100 ng/ml. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 20 mM PB, pH 7.4, 150 mM NaCl. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Rat GRO alpha/CXCL1 (rRtGRO-α/CXCL1) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability Lyophilized recombinant Rat GRO alpha/CXCL1 (rRtGRO-α/CXCL1) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background CXCL1 plays a major role in inflammation, angiogenesis, tumorigenesis, and wound healing. CXCL1 is shown to be up-regulated in melanoma cells, and it is involved in pathogenesis of melanoma[1]. |
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