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Recombinant Human GRO gama/CXCL3

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132710-10 μg 0 ￥4400 请登录
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1308132710-50 μg 0 ￥11600 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human GRO gama/CXCL3 通过与细胞表面趋化因子受体相结合作用介导其对靶细胞的影响。
Synonyms
rHuGRO-γ/CXCL3; C-X-C motif chemokine 3; MIP2-beta ; 重组人 CXC 趋化因子3
Species
Human

Source
E. coli

Accession
P19876

Gene ID
2921

Molecular Weight
Approximately 7.9 kDa

AA Sequence
ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN

Biological Activity
Full biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100 ng/mL.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against 20 mM PB, pH 7.4, 50 mM NaCl.

Endotoxin Level
<1 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human GRO gama/CXCL3 (rHuGRO-γ/CXCL3) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA.

Storage & Stability
Lyophilized recombinant Human GRO gama/CXCL3 (rHuGRO-γ/CXCL3) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
CXCL3 is a small cytokine belonging to the CXC chemokine family that is also known as GRO3 oncogene (GRO3). CXCL3 controls migration and adhesion of monocytes and mediates its effects on its target cell by interacting with a cell surface chemokine receptor called CXCR2[1]. CXCL3 also regulates cell autonomously the migration of the precursors of cerebellar granule neurons toward the internal layers of cerebellum, during the morphogenesis of cerebellum[2].
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