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Recombinant Rhesus Macaque Interleukin-1 beta

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132720-10 μg 0 ￥4200 请登录
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1308132720-50 μg 0 ￥13000 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Rhesus Macaque Interleukin-1 beta 能调控炎症反应，参与细胞增殖、分化、凋亡等多种细胞生命活动。
Synonyms
rRhIL-1β; IL1B ; 重组恒河猴白细胞介素-1 β
Species
Rhesus Macaque

Source
E. coli

Accession
P48090

Gene ID
704701

Molecular Weight
Approximately 17.3 kDa

AA Sequence
APVRSLHCTL RDAQLKSLVM SGPYELKALH LQGQDLEQQV VFSMSFVQGE ESNDKIPVAL GLKAKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTRGG QDITDFTMQF VSS

Biological Activity
The ED50 is <10 pg/mL as measured by murine D10.G4.1 cells, corresponding to a specific activity of >1.0 × 108 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS, pH 7.4.

Endotoxin Level
<1 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Rhesus Macaque Interleukin-1 beta (rRhIL-1β) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA.

Storage & Stability
Lyophilized recombinant Rhesus Macaque Interleukin-1 beta (rRhIL-1β) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
IL1β is apro-inflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. IL1β bind to the same receptor and have similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the ability to stimulate the release of prostaglandin and collagenase from synovial cells[1]
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