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Recombinant Human Interleukin-17F

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132722-10 μg 0 ￥3800 请登录
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1308132722-50 μg 0 ￥8400 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human Interleukin-17F 在炎症反应中有多种功能，在一些肿瘤发生过程中起保护作用。
Synonyms
rHuIL-17F; Cytokine ML-1 ; 重组人白细胞介素-17F
Species
Human

Source
E. coli

Accession
Q96PD4

Gene ID
112744

Molecular Weight
Approximately 30.1 kDa

AA Sequence
MRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ

Biological Activity
The ED50 is <20 ng/mL as measured by murine NIH/3T3 cells, corresponding to a specific activity of >5.0 × 104 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS, pH 7.2, with trehalose.

Endotoxin Level
<1 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Interleukin-17F (rHuIL-17F) to 100 μg/mL using 4 mM HCl.

Storage & Stability
Lyophilized recombinant Human Interleukin-17F (rHuIL-17F) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Recombinant Human Interleukin-17F could induce pulmonary neutrophilia and amplifies antigen-induced allergic response[1]. IL-17F has been shown to have multiple functions in inflammatory responses and plays an important role in the tumorigenesis of human colonic epithelial cells.. Similar to IL-17A, IL-17F induces the production of many pro-inflammatory cytokines (IL-6/GM-CSF) and chemokines (CXCL1/2/5) in different cell types, as well as enhances granulopoiesis and neutrophil recruitment[2].
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