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Recombinant Human LD78 beta/CCL3L1

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132743-10 μg 0 ￥3200 请登录
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1308132743-50 μg 0 ￥7800 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human LD78 beta/CCL3L1是HIV-1共受体CCR5的有效配体，其对于病毒进入人宿主细胞是必需的。
Synonyms
rHuLD78β/CCL3L1; C-C motif chemokine 3-like 1; SCYA3L1 ; 重组人LD78 beta/CCL3L1
Species
Human

Source
E. coli

Accession
P16619

Gene ID
6349

Molecular Weight
Approximately 7.8 kDa

AA Sequence
APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA

Biological Activity
The ED50 is <0.4 μg/mL as measured by CHO cells, corresponding to a specific activity of >2.5 × 103 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human LD78 beta/CCL3L1 (rHuLD78β/CCL3L1) to 100 μg/mL using ddH2O.

Storage & Stability
Lyophilized recombinant Human LD78 beta/CCL3L1 (rHuLD78β/CCL3L1) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
CCL3L1 is the most potent known ligand for CC chemokine receptor 5 (CCR5), the major coreceptor for HIV, and it is a dominant HIV-suppressive chemokine. Possession of a CCL3L1 copy number lower than the population average is associated with markedly enhanced HIV/acquired immunodeficiency syndrome (AIDS) susceptibility[1].
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