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生化科研试剂 >> 抗体产品 >> 一抗 |
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Alpha-Tubulin Rabbit Monoclonal IgG |
别 名: |
Tubulin alpha-ubiquitous chain,
Alpha-tubulin ubiquitous, Tubulin K-alpha-1 |
货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
1227177527 |
Alpha-Tubulin |
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100ul |
询价 |
现货 |
3天 |
提示信息:偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体,下单前请联系客服。 |
性 状: |
【反应特异性】Human , Mouse , Rat 【克隆 ID】EP1332Y 【用途】WB , IHC , ICC , IP 【抗原分子量】50 kDa
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质量标准: |
【产品介绍】Microtubules are essential parts in eukaryotic cell structures, transp o r tation, a n d mitosis. It consists mainly of 2 soluble protein subunits, alpha a n d beta tubulin. Beta tubulin binds to alpha tubulin to f o r m tubulin heterodimer which is post-translationally modified (1). The tubulin dimer complex binds to GTP a n d assembles onto the positive ends of microtubules. After inc o r p o r ation into the microtubules, bound GTP is hydrolyzed by beta tubulin. The stability of the dimer in the microtubules is depended on presence of beta tubulin, where dimer with GTP bound beta-tubulin is stable to microtubule inc o r p o r ation (2). F o r both type of tubulin, the carboxy-terminal tail is pos-translationally modified to regulate associated protein binding at microtubule surface (3). A mutation on alpha tubulin has been linked to abn o r mal neuronal migration a n d neurodevelopmental dis o r ders in human (4). WB: 1:50,000 IHC: 1:250 500 ICC: 1:250 500 Flow Cytometry: 1:20 IP: 1:50
A. Western blot analysis on HeLa cell lysate using anti- α-Tubulin RabMAb (cat. # 1878-1), dilution 1:50,000. B. Immunohistochemical analysis of paraffin-embedded human gastric carcinoma using anti- α-Tubulin RabMAb (cat# 1878-1). A. Imunoflu o r escent staining of HeLa cells using anti- α-Tubulin RabMAb (cat# 1878-1)
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