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Alpha-Tubulin Phospho (pY272) (TUBA1B)

英文名：Rabbit Monoclonal Antibody
Cas号：
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别 名 TUBA1B antibody, K-ALPHA-1 antibody, Tubulin alpha-1B chain antibody, Alpha-tubulin ubiquitous antibody, Tubulin K-alpha-1 antibody, Tubulin alpha-ubiquitous chain antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Tubulin is the major constituent
of microtubules. It binds two moles of GTP, one at
an exchangeable site on the beta chain and one at
a non-exchangeable site on the alpha-chain. An
essential component of microtubules, alpha-tubulin is also
a multigene family in many species (1).
Familial amyloidosis, British type, is an autosomal
dominant disease characterized by progressive
dementia, spastic paralysis and ataxia. The identity of
the accumulating amyloid is not known, thus preventing
the definitive classification of the disease.
Findings suggest that the C-terminal fragments of
both alpha- and beta-tubulin are closely associated to
the amyloid deposits of familial amyloidosis, British
type (2).


Recommended Applications

WB, ICC
Applications and Recommended Dilution Factors

WB: 1:25,000
ICC: 1:50 - 100
Species Reactivity *

Human

*Cross reactivity determined by western blot only.

Products Data
A. Western blot analysis on Jurkat cell lysates
using anti-Phospho-Alpha-Tubulin (p272) RabMAb
(cat. #2243-1), 1:50,000 dilution. Cells were
either (A) untreated (B) treated with pervanadate.

Specificity

A phospho synthetic peptide corresponding to
residues surrounding tyrosine 272 of human alpha-tubulin
was used as an immunogen. This antibody detects
alpha-tubulin phosphorylated at tyrosine 272.
性状 【反应特异性】Human
【克隆 ID】EP1334(2)Y
【用途】WB , ICC
【抗原分子量】52kDa
贮存 Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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