Antithrombin III (SERPINC1)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 SERPINC1 antibody, AT3 antibody, ATIII antibody, MGC22579 antibody, Antithrombin-III antibody, Serpin C1 antibody
Cas号
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分子式
分子量
产品参数 【产品介绍】Antithrombin III is a plasma protease
inhibitor and a member of the serpin superfamily.
It inhibits thrombin as well as other activated
serine proteases of the coagulation system, and it
regulates the blood coagulation cascade. Antithrombin
III includes two functional domains: the heparin
binding-domain at the N-terminus of the mature protein,
and the reactive site domain at the C-terminus.
The inhibitory activity is enhanced by the presence
of heparin. More than 120 mutations have been
identified, many of which are known to
cause antithrombin-III deficiency (1).


Recommended Applications

WB, IHC, IP
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:50 - 100
IP: 1:10 - 100
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.


Products Data
Western blot analysis on (A) human plasma, (B) human
ovary cancer, (C) human testis, and (D) fetal lung
lysates using anti-Antithrombin III RabMAb (cat. #5477-1).

Immunohistochemical analysis of paraffin-embedded
human liver tissue using anti-Antithrombin III RabMAb
(cat. #5477-1).

Specificity

A synthetic peptide corresponding to residues in
human Antithrombin III was used as an immunogen.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EP5372
【用途】WB , IHC , IP
【抗原分子量】55kDa
贮存 Storage Condition and Buffer Store at -20° C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
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