BRG1 (SMARCA4)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 SMARCA4 antibody, BAF190 antibody, BRG1 antibody, FLJ39786 antibody, RTPS2 antibody, SNF2 antibody, SNF2-BETA antibody, SNF2L4 antibody, SNF2LB antibody, SWI2 antibody, hSNF2b antibody, Transcription activator BRG1 antibody, Mitotic growth and transcripti
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】BRG1 protein (brahma-related gene 1) is a
member of SWI/SNF family which mediates
ATP-dependent chromatin remodeling processes. BRG is
a central catalytic ATPase of the SWI/SNF
chromatin-remodeling complex, where it uses the
energy derived from ATP-hydrolysis to disrupt the
chromatin architecture of target promoters. Considered
a major co-regulator of transcription, BRG1 has
been implicated in the activation and repression of
gene expression through the modulation of chromatin
in various tissues and physiological conditions.
BRG1 appears to be a critical modulator of
transcriptional regulation in cellular processes such
as transcriptional regulation, replication, DNA repair
and recombination (1, 2).


Recommended Applications

WB, IHC, ICC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 5,000
IHC: 1:100 - 250
ICC: 1:100 - 250
Species Reactivity *

Human

*Cross reactivity determined by western blot only.

Products Data

Western blot analysis on A) K562 and B) Molt-4 cell
lysates using anti-BRG1 RabMAb (cat. #2776-1).

Immunofluorescent staining of HeLa cells using
anti-BRG1 RabMAb (cat# 2776-1)

Immunohistochemical analysis of paraffin-embedded
human colon tissue using anti-BRG1 RabMAb (cat# 2776-1)

Specificity

A synthetic peptide corresponding to residues of human
BRG1 protein was used as an immunogen

性状 【反应特异性】Human
【克隆 ID】EPR3912
【用途】WB , IHC , ICC
【抗原分子量】200kDa

贮存 Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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