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Btk (C-term)
英文名:Rabbit Monoclonal IgG
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113379-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | PR12, Nucleic acid-binding regulat o r y protein |
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产品参数 | 【产品介绍】Btk (Bruton tyrosine kinase also known as BPK
o r ATK) is a member of the TEC family of non-recept o r protein tyrosine kinase which includes Bmx, Itk a n d TEC. Btk is composed of a pleckstrin domain, an SH3 a n d SH2 domain, a catalytic kinase domain a n d a TEC homology domain (1). BTK plays a crucial role in B cell activation a n d development (2). Similar to Etk-TNFR2 interaction, Btk interacts with Fas, a member of the TNFR family involved in apoptosis in a lig a n d -independent manner (3) Mutations in the Btk gene have been linked to severe developmental blocks in human B-cell ontogeny leading to X-linked agammaglobulinemia (XLA). Patients with this disease are unusually prone to bacterial infection but not to viral infection. WB: 1:500 IP: 1:20 A. Western blot analysis on Daudi cell lysate using anti-Btk (C-term) RabMAb (cat. #1599-1), 1:500 dilution |
性状 | 【反应特异性】Human
【克隆 ID】Y440 【用途】WB , IP 【抗原分子量】77 kDa |
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