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Cystatin B (CSTB)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113476-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | CSTB antibody, CST6 antibody, EPM1 antibody, PME antibody, STFB antibody, Cystatin-B antibody, CPI-B antibody, Liver thiol proteinase inhibitor antibody, Stefin-B antibody |
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| 产品参数 | 【产品介绍】Cystatin B is a member of the cysteine
protease inhibitor superfamily, functioning as an intracellular protease inhibitor (1). It plays a role in inhibiting cysteine proteinases and protecting proteinases from lysosomal leakage (1, 2). The second hairpin loop and the C-terminal end of Cystatin B anchor the inhibitor to target proteinases (3). A deficiency in cystatin B is observed in progressive myoclonic epilepsy type 1 (1). This deficiency predisposes neurons to oxidative stress that leads to neuronal death and degeneration (1). In addition, Cystatin B has been linked to amyloid fibril formation in vitro and is overexpressed in hepatocellular carcinoma (4, 5). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1: 1,000 - 10,000 ICC: 1: 250 - 500 Species Reactivity Human Products Data Western blot analysis on (A) human bladder and (B) U87-MG cell lysates using anti-Cystatin B RabMAb (cat. # 2842-1). Specificity A synthetic peptide corresponding to residues in human Cystatin B was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR3930 【用途】WB , ICC 【抗原分子量】11kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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