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CSTB antibody
英文名:Rabbit Monoclonal Antibody
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货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113477-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | Cystatin B (CSTB), CST6 antibody, EPM1 antibody, PME antibody, STFB antibody, Cystatin-B antibody, CPI-B antibody, Liver thiol proteinase inhibitor antibody, Stefin-B antibody |
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产品参数 | 【产品介绍】Cystatin B is a member of the cysteine
protease inhibitor superfamily, functioning as an intracellular thiol protease inhibitor (1). It plays a role in protecting proteinases from lysosomal leakage (1, 2). The second hairpin loop and the C-terminal end of Cystatin B anchor the inhibitor to target proteinases (3). Cystatin B interacts with and inhibits proteases of the cathepsin family (4). A deficiency in cystatin B is observed in progressive myoclonic epilepsy type 1 (1). This deficiency predisposes neurons to oxidative stress that leads to neuronal death and degeneration (1). In addition, Cystatin B has been linked to amyloid fibril formation in vitro and is overexpressed in hepatocellular carcinoma (5, 6). Recommended Applications WB, IHC, FC Applications and Recommended Dilution Factors WB: 1:1,000-10,000 IHC: 1:100 - 250 FC: 1:10 - 100 Species Reactivity Human, Rat Products Data Western blot analysis on (A) U87-MG, (B) JAR, and (C) human bladder cell lysates using anti-Cystatin B RabMAb (cat. # 2821-1). Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-Cystatin B RabMAb (cat. #2821-1). Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Cystatin B RabMAb (cat. #2821-1). Specificity A synthetic peptide corresponding to residues in human Cystatin B was used as an immunogen. |
性状 | 【反应特异性】Human , Rat
【克隆 ID】EPR3931 【用途】WB , IHC , FC 【抗原分子量】11kDa |
贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |