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Cytochrome P450 17A1 (CYP17A1)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113480-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | CYP17A1 antibody, CPT7 antibody, CYP17 antibody, P450C17 antibody, S17AH antibody, Steroid 17-alpha-hydroxylase/17,20 lyase antibody, Steroid 17-alpha-monooxygenase antibody |
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| 产品参数 | 【产品介绍】Cytochrome P450 17A1 is a member of
the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. It localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in Cytochrome P450 17A1 are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia (1). Recommended Applications WB, ICC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:100 - 250 IP: 1:10 - 100 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) human adrenal gland, (B) SK-OV-3, (C) HeLa, and (D) Jurkat lysates using anti-Cytochrome P450 17A1 RabMAb (cat. #5419-1). Immunofluorescent staining of HeLa cells using anti-Cytochrome P450 17A1 RabMAb (cat.# 5419-1). Specificity A synthetic peptide corresponding to residues in human Cytochrome P450 17A1 was used as an immunogen. |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6293 【用途】WB , ICC , IP 【抗原分子量】55kDa |
| 贮存 | Storage Condition and Buffer Store at -20° C. Buffer: PBS (pH 7.2), 50% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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