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Recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12

英文名：
Cas号：
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货号 规格 货期 库存 价格 会员价 订购
1308132795-10 μg 0 ￥4200 请登录
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1308132795-50 μg 0 ￥11800 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12 是 CXC 趋化因子家族成员，能够结合 CXCR4、CXCR7，与肿瘤的增殖、存活、血管生成、转移及免疫抑制有关。
Synonyms
rMuSDF-1α/CXCL12; C-X-C motif chemokine 12; PBSF ; 重组小鼠基质细胞衍生因子-1α/CXCL12
Species
Mouse

Source
E. coli

Accession
P40224

Gene ID
20315

Molecular Weight
Approximately 8.0 kDa

AA Sequence
KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK

Biological Activity
Full biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 50-100 ng/ml.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS, pH 7.4.

Endotoxin Level
<1 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12 (rMuSDF-1α/CXCL12) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA.

Storage & Stability
Lyophilized recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12 (rMuSDF-1α/CXCL12) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
CXCL12 belongs to the CXC chemokine family, and is expressed in two isoforms, SDF-1α and SDF-1β, binds to CXCR4 and CXCR7. CXCL12/CXCR4 signal is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression[1].
贮存
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