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Recombinant Human Platelet factor-4/CXCL4 (HEK293-expressed)
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性状 | Recombinant Human Platelet factor-4/CXCL4 (HEK293-expressed) 是 CXC 趋化因子家族成员,具有抗肝素、抗血管生成的活性,同时可抑制肿瘤新生血管形成。
Synonyms rHuPF-4/CXCL4; C-X-C motif chemokine 4; Oncostatin A; SCYB4 ; 重组人血小板因子-4/CXCL4 (HEK293 细胞表达) Species Human Source HEK 293 Accession P02776 Gene ID 5196 Molecular Weight Approximately 7.8 kDa AA Sequence EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES Biological Activity The ED50 is <10 μg/mL as measured by its ability to inhibit human FGF-basic-dependent proliferation of NR6R 3T3 mouse fibroblast cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Platelet factor-4/CXCL4 (HEK293-expressed) (rHuPF-4/CXCL4) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Human Platelet factor-4/CXCL4 (HEK293-expressed) (rHuPF-4/CXCL4) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background PF-4/CXCL4 is a member of the CXC chemokine family produced by cells of the megakaryocytic lineage. CXCL4 has antiheparin activity, responsible for the important role of CXCL4 in the regulation of coagulation processes. CXCL4 has exhibits antiangiogenic properties in vitro and in vivo and inhibits tumor neovascularization through a variety of mechanisms[1]. |
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- Recombinant Mouse Platelet-Derived Growth Factor-AA
- Recombinant Rat Platelet-Derived Growth Factor-BB
- Recombinant Human PDGF-CC (HEK293-expressed)
- Recombinant Human PDGF-DD (CHO-expressed)
- Recombinant Human Platelet factor-4/CXCL4 (HEK293-expressed)
- Recombinant Human RANTES/CCL5 (HEK293-expressed)
- Recombinant Human Stromal-Cell Derived Factor-1 alpha/CXCL12
- Recombinant Mouse Stromal-Cell Derived Factor-1 alpha/CXCL12
- Recombinant Rat Stromal-Cell Derived Factor-1 alpha/CXCL12