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Recombinant Human PDGF-DD (CHO-expressed)

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132791-10 μg 0 ￥3200 请登录
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1308132791-50 μg 0 ￥9800 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human PDGF-DD (CHO-expressed) 属于 PDGF 家族，能够特异性地结合并激活其同源受体 PDGFR-β，通过激活多个下游致癌途径参与调节肿瘤增殖、转化和侵袭，导致肿瘤发展。
Synonyms
rHuPDGF-DD; Platelet-derived growth factor D; SCDGFB ; 重组人血小板衍生生长因子-DD (CHO 细胞表达)
Species
Human

Source
CHO

Accession
Q9GZP0

Gene ID
80310

Molecular Weight
19-21 kDa

AA Sequence
SYHDRKSKVD LDRLNDDAKR YSCTPRNYSV NIREELKLAN VVFFPRCLLV QRCGGNCGCG TVNWRSCTCN SGKTVKKYHE VLQFEPGHIK RRGRAKTMAL VDIQLDHHER CDCICSSRPP R

Biological Activity
The ED50 is <5 μg/mL as measured by 3T3 cells.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human PDGF-DD (CHO-expressed) (rHuPDGF-DD) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Human PDGF-DD (CHO-expressed) (rHuPDGF-DD) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
PDGF-DD is a member of the PDGF family, specifically binds to and activates its cognate receptor PDGFR-β, and participates in regulating cancer proliferation, transformation, and invasion through activating multiple downstream oncogenic pathways, resulting in tumor development and progression[1].
贮存
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
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