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Recombinant Human RANTES/CCL5 (HEK293-expressed)

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132793-5 μg 0 ￥2200 请登录
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1308132793-25 μg 0 ￥5300 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human RANTES/CCL5 (HEK293-expressed) 是一种有效的 CC 趋化因子，在类风湿性关节炎发病机理中具有重要作用。
Synonyms
rHuRANTES/CCL5; C-C motif chemokine 5; SCYA5 ; 重组人 RANTES/CCL5 (HEK293 细胞表达)
Species
Human

Source
HEK 293

Accession
P13501

Gene ID
6352

Molecular Weight
Approximately 8 kDa

AA Sequence
SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS

Biological Activity
The ED50 is <0.2 μg/mL as measured by CHO-K1/Gα15/hCCR1 cells (human Gα15 and human CCR1 stably expressed in CHO-K1 cells).

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human RANTES/CCL5 (HEK293-expressed) (rHuRANTES/CCL5) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Human RANTES/CCL5 (HEK293-expressed) (rHuRANTES/CCL5) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
RANTES/CCL5 is a potent CC chemokine shown to play an important role in rheumatoid arthritis pathogenesis. RANTES/CCL5 primarily attracts lymphocytes and monocytes as well as other cell types. Rheumatoid arthritis synovial fibroblasts produce RANTES/CCL5 upon stimulation with TNF-α, IL-1β, or interferon gamma[1].
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